veuillez trouvez une proposition de
post-doc/ doc, dans le domaine du traitement du signal
appliqué à des enregistrements chroniques, in vivo, de
patients épileptiques éveillés,
utilisant des microélectrodes et des macroélectrodes
intracérébrales.
La thématique de recherche est centrée
autour de la physiopathologie de
l’épilepsie, avec analyse multi niveaux des signaux que
nous obtenons en LFP/multiunits et Single Unit, à
différentes périodes
(crises/ intercritique/
précritique)
N’hésitez pas à faire circuler cette offre
Bien cordialement,
Vinent Navarro, MD, PhD
Postdoctoral position : Pathophysiology
of epilepsy- in vivo microelectrodes recordings
Institut du Cerveau et de la Moelle
Epinière, Paris, France
The « EpiMicro » group,
within the Pr Stephane Charpier’s team, at the Brain and
Spine Institute (ICM) in Paris, is looking for a
postdoctoral fellow to participate in a project on
intracerebral recordings with macro and microelectrodes in
epileptic patients. The ICM is a newly created institute
focusing on basic and translational research in neuroscience
and is located in the heart of Paris within the largest
European hospital.
The general goal of this project is to improve
knowledge on pathophysiology of epilepsy, in particular the
interictal events and the epileptic seizures. With the
development of intracerebral recordings with microelectrodes
for many years in our epileptic patients, we are now able to
perform intracerebral recordings at different scales, from
usual macroelectrodes to unique neuron recordings, in the
interictal period but also during seizures, in multiple
intracerebral areas.
The primary role of the position will be to
perform electrophysiological analysis of intracerebral datas
at different periods: during the interictal period and
preictal period and to study the link with multiunit
activities in cortical areas. The project will concern human
partial epilepsy and also animal models of epilepsy. We are
currently studying the dynamics of seizure emergence in
different models of mice and rat.
The doc /post-doc will be integrated in a
multidisciplinary team including researchers, engineers,
clinical electrophysiologists, neuroradiologists and
neurosurgeons. He/she will receive assistance for an
engineer for the data acquisition and storage. In addition,
he/she will have inputs from several researchers in methods
of signal analysis.
The postdoctoral fellow will have
responsibilities for data analysis and preparation of
scientific publications.
The candidate should
have a PhD or equivalent in Signal analysis or Neuroscience
related field. Expertise in signal processing and good
analytical skills (MATLAB) are required. Since the analytic
approaches needed for this study have been extensively
developed and used in animals, experience in animal
in vivo or in vitro experiments is a plus.
The starting date is April
2016. The proposition is for an initial period of 24
months with possible renewal (total of
3 years). The competitive salary will be according to
experience. The candidate will also have access to the
French system benefits.
Keywords :
intracerebral recordings, microelectrodes, epileptic
patients
Pr Vincent
Navarro